serum igf1 concentration (R&D Systems)
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Serum Igf1 Concentration, supplied by R&D Systems, used in various techniques. Bioz Stars score: 99/100, based on 383 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 99 stars, based on 383 article reviews
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1) Product Images from "Dexamethasone exposure during pregnancy triggers metabolic syndrome in offspring via epigenetic alteration of IGF1."
Article Title: Dexamethasone exposure during pregnancy triggers metabolic syndrome in offspring via epigenetic alteration of IGF1.
Journal: Cell communication and signaling : CCS
doi: 10.1186/s12964-024-01472-6
Figure Legend Snippet: Fig. 3 Effects of prenatal dexamethasone exposure (PDE) on the fetal liver development and the levels of corticosterone (CORT) and insulin-like growth factor 1(IGF1). A Fetal body weight and intrauterine growth retardation (IUGR) rate (n = 8); (B) Hematoxylin and eosin (H&E) staining of the fetal liver (Scale bar = 500 μm); (C) Ki67-stained nuclei and quantitative analysis (Scale bar = 500 μm); (D) The mRNA expression of hepatic development-related genes (n = 8); (E) Serum CORT level (n = 8); (F) Serum IGF1 level (n = 8); (G) The mRNA expression of IGF1 signaling pathway (n = 8). Mean ± S.E.M. *P < 0.05, **P < 0.01 vs. the control group. NS, no significance; PDE(L), prenatal dexamethasone exposure at a low dose (0.2 mg/ kg∙d); PDE(H), prenatal dexamethasone exposure at a high dose (0.8 mg/kg∙d)
Techniques Used: Staining, Expressing, Control
Figure Legend Snippet: Fig. 4 Effects of prenatal dexamethasone exposure (PDE) on postnatal liver development and the levels of corticosterone (CORT) and insulin-like growth factor 1(IGF1) at postnatal week (PW) 6 and 12. A The mRNA expression of liver development-related genes at PW6 (n = 8); (B) Serum CORT at PW6 (n = 8); (C) Serum IGF1 level at PW6 (n = 8); (D) The mRNA expression of liver IGF1 signaling pathway expression at PW6 (n = 8); (E) Serum CORT with or without unpredictable chronic stress (UCS) at PW12 (n = 8); (F) Serum IGF1 level with or without UCS at PW12 (n = 8); (G) The mRNA expression of liver IGF1 signaling pathway expression with or without UCS at PW12 (n = 8); (H) The mRNA expression of liver development-related genes with or without UCS at PW12 (n = 8). Mean ± S.E.M. *P < 0.05, **P < 0.01 vs. the control group. NS, no significance; PDE(L), prenatal dexamethasone exposure at a low dose (0.2 mg/kg∙d)
Techniques Used: Expressing, Control
Figure Legend Snippet: Fig. 6 Effects of prenatal dexamethasone treatment (PDT) on the body weight, serum hepatic function markers, serum cortisol level, and serum insulin-like growth factor 1 (IGF1) level of the male neonates. A Neonatal body weight (n = 18); (B) Serum albumin (ALB) (n = 18); (C) Serum alpha-fetoprotein (AFP) (n = 18); (D) The ratio of ALB to AFP (n = 18); (E) Serum cortisol level (n = 18); (F) Serum IGF1 level (n = 18); (G) The correlation analysis between serum cortisol and IGF1; Mean ± S.E.M. *P < 0.05, **P < 0.01 vs. the control group. NS, no significance
Techniques Used: Control
Figure Legend Snippet: Fig. 7 Dexamethasone exposure during pregnancy triggers metabolic syndrome in offspring via epigenetic alteration of IGF1. GC, glucocorticoid; GRα, glucocorticoid receptor α; SP1, special protein 1; IGF1, insulin-like growth factor 1; H3K27ac, histone 3 lysine 27 acetylation
Techniques Used: